- John Garland Pollard Papers, 1683/1968, bulk 1856/19371
- John Marshall Papers, 1755/18351
- John Murray, 4th Earl of Dunmore Papers, 1768/18041
- John Tayloe Perrin Papers, 1770/19311
- Jonathan Boucher papers, 1759/18031
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Mary and Hannah Gibbons Papers, 1743/18901
- Maupin-Washington Papers, 1732/19321
- McGavock Family Papers, 1760/18881
- Michael La Vean French documents collection, 1751/18511
- Mills E. Godwin, Jr. Papers, 1712/1989, bulk 1947/19891
- Myron Schmall Collection, 1711/18151
- Overton family papers, 1727/1961, bulk 1781/18751
- Peter Goelet Papers, 1762/1886, bulk 1770/17791
- Preston Family Papers, 1755/1836, bulk 1786/18151