- Alexander Brown Papers (II), 1748/19001
- Armistead-Cocke Papers, 1680/19171
- Baer Family Papers, 1744/19291
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Blair Family Papers, 1741/17921
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Brafferton Estate Collection, 1691/19351
- C. L. Worthington Papers, 1752/19381
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Campbell Family Papers, 1726/19201
- Carl R. Dolmetsch Papers, 1751/19901
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Charles Campbell Papers, 1743/18961
- Colvin Papers, 1734/18391