- Armistead-Cocke Papers, 1680/19171
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Brafferton Estate Collection, 1691/19351
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Dunmore Family Papers (I) [in part photocopies], 1650/18991
- George Mason Papers, 1706/18581
- Hugh Jones Collection, 1716/19431
- John Garland Pollard Papers, 1683/1968, bulk 1856/19371
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Mills E. Godwin, Jr. Papers, 1712/1989, bulk 1947/19891
- Myron Schmall Collection, 1711/18151
- Office of the President. James Blair Records, 1695/17471