- Davis Family Papers, 1800/19411
- George Ellis Moore Manuscript, 19632
- Gibson Lamb Cranmer Papers regarding Statehood and Other Material, 1787/1895, bulk 1822/18811
- H.E. Matheny, Collector and Compiler, Civil War Correspondence and Other Material, 1861/18651
- H.E. Matheny, Collector and Compiler, Papers, 1956/19611
- Henri Jean Mugler Diary and Memoir, 1838/18991
- Isaac McNeel (b.1830) Papers, 1850/19081
- J. Hughes, Letter Regarding Response of Berkeley County Citizens to the Ordinance of Secession, 18611
- John J. Davis (1824-1916) Papers, 1824/19351
- Lewis (1778-1843) and George W. (1804-1868) Summers Papers, 1828/19351
- Powell Benton Reynolds (1841-1914) Correspondence, 1861/18641
- Powell Benton Reynolds (1841-1914) Correspondence, 1861/18851
- Siler Family Papers, 1848/19681
- William Gaston Caperton (1815-1852) Family Papers, 1801/19301