- Alfred R. Armstrong Papers, 1928/19761
- Amelia Jastrebski Perkins and Charles S. Perkins, Jr. Papers, 1936/19451
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651
- Ann Louise Clarke Scrapbook, 1930/19431
- Arthur W. and Leah James Scrapbooks, 1909/19771
- Barbara Ruth Bevan Papers, 19411
- Board of Visitors records, 1757/20231
- Career Center Records, 1939/2001, bulk 1950/19851
- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/19741
- Catherine Dennis Papers, 1918/1974, bulk 1918/19211
- Chi Omega (Omicron Beta Chapter) Records, 1921/20121
- Class Histories and Activities collection, 1905/20141
- Class of 1943 Scrapbook, 1939/19431
- College Rules Collection, 1849/19551
- College of William and Mary Directory Collection, 1827/20131