- Adam Empie Papers, 1811/2004, bulk 1811/18501
- Alumni Association Records, 1833/2014, bulk 1950/20051
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Board of Visitors records, 1757/20231
- Borland Family Papers, 1771/19401
- College Papers Collection, 1880/19991
- Commencement Exercises collection, 1831/20241
- Edwin Taliaferro Collection, 1860/19711
- Faculty Assembly Records, 1729/20081
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Hall Family Papers, 1810/20071
- Henry Denison Cole Papers, 1786/19391
- John Millington Papers, 1801/19511
- Office of the Bursar Records, 1739/19871
- Office of the President, John Augustine Smith Records, 1814/1944, bulk 1814/18261