- Black, Kent, and Apperson Family Papers, 1779/19841
- Charles W. Crush Collection, 1796/19781
- Daniel Bedinger Lucas Papers, 1812/18241
- Earhart Family Papers, 1788/19281
- Henry Iddings Family Collection, 1810/19001
- Huff-Hylton Families Papers, 1803/19751
- Jamerson-Webster-Basham Family Papers, 1792/19361
- John Janney Papers, 1811/1994, bulk 1840/18801
- Key Family Papers, 1812/19041
- Nelson Family Papers, 1783/18721
- Richards-Woody Family Papers, 1803/19921
- Stearns Family Papers, 1714/19201
- Virginia Elections Collection, 1804/18651
- William E. Hoge Family Papers, 1810/19331
- Yancey Family Papers, 1808/19121