- A. Philip Randolph, Civil Rights and Labor Leader, Papers, 1919/19371
- American Missionary Society Papers, 1848/18821
- Brown Family Papers, Photographs and Maps, 1765/19591
- David R. Preston Diary, 1828/18291
- Dawson Coal Company Collection, 1917/19481
- Dr. William H. Waddell, Veterinarian and Author, Records, 1938/19871
- Ebenezer Wilson Patton Papers, 1869/18791
- Edward J. Cabbell, Historian, Papers, 1969/19881
- First Baptist Church of Parkersburg Records, 1817/19101
- General Education Board Records, 1901/19671
- Gibson Lamb Cranmer Papers regarding Statehood and Other Material, 1787/1895, bulk 1822/18811
- Gordon B. Gibbens Papers, 1878/19021
- H.E. Matheny, Collector and Compiler, Papers, 1956/19611
- Henry Ruffner (1790-1861) and William Henry (1824-1908) Papers, 1829/19131
- Jacob H. Gerbrick, Photographer, Records, 1857/19741