- Benjamin Waller Account Book, 1803/18331
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Brooke County (W. Va.) Court Records and Miscellaneous Papers, 1780/19181
- C. L. Worthington Papers, 1752/19381
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Campbell Family Papers, 1795/18731
- Catesby Jones Account Book, 1767/18451
- Chappelear Collection, 1788/19591
- Charles Campbell Papers, 1743/18961
- Christopher Tompkins Papers, 1778/18381
- Clarence Edwin Smith (1885-1959) Papers, 1787/19572
- Cloverdale Furnace (Botetourt County, Va.), 1803/18051
- Cornelius Smith Papers, 1805/18901
- Courtney Family Papers, 1804/19201
- Daniel Philippe Aunspaugh Papers, 1800/18811