- C. Harrison Mann, Jr. Map Collection, 1579/19611
- Claude Moore Health Sciences Library records, 1848/2019, bulk 1942/20251
- Collection of W. W. Yen materials, 1899/19741
- Folk Art Herbarium album, 1907/19131
- Herbert Friedman Holocaust materials, 1924/20061
- Hugh Carr family papers and River View Farm, 1843/19784
- Jefferson Cable Corporation collection, 1885/19821
- John Augustine Washington III and Mount Vernon Ladies' Association (MVLA) collection, 1834/19571
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/18654
- Law examinations - University of Virginia School of Law, 1890/20181
- Ledger Bethel Amateur Literary and Dramatic Club and Westview Farm, 1885/19331
- Madison Friendship Lodge Grand United Order of Odd Fellows collection, 1880/19377
- Molka Reich papers, 1904/19861
- Quinby, Teackle, and Upshur families of Somerset County, Maryland, and Accomack and Northampton Counties, Virginia Papers, 1713/19771
- Superintendent's Letter Books, Diaries, and Monthly Reports - collection of bound volumes, 1885/196716