- Anna Maria Hickman Otis Mead Chalmers family papers1
- C. Harrison Mann, Jr. Map Collection1
- Claude Moore Health Sciences Library records1
- Hugh Carr family papers and River View Farm2
- Jefferson Cable Corporation collection1
- John Augustine Washington III and Mount Vernon Ladies' Association (MVLA) collection1
- John L. Nau III Civil War History Collection5
- Ledger Bethel Amateur Literary and Dramatic Club and Westview Farm1
- Madison Friendship Lodge Grand United Order of Odd Fellows collection5
- Quinby, Teackle, and Upshur families of Somerset County, Maryland, and Accomack and Northampton Counties, Virginia Papers1
- Superintendent's Letter Books, Diaries, and Monthly Reports - collection of bound volumes9
- The University of Virginia Collection on the History of Childhood, Parenting, and Family Building.1
- The University of Virginia Jefferson Papers3
- University of Virginia School of Medicine records1
- Watts family papers-addition1