- Abraham Anson papers1
- Blackley Family papers1
- Blanche Lazzell, Artist, Papers1
- Booker T. Washington, Commemorative Articles and Other Miscellaneous Items1
- Charles Lietwiler transportation collection1
- Connie Smith family photograph album1
- Dr. J.C. Easton, History Professor, Papers1
- Duncan Alexander MacLeod Collection1
- Earl Ray Zinn Papers1
- Ephemera Collection1
- George Kossuth, Photographer, Photographs1
- Gravely and Moore Studio, Photography Business in Charleston, Negatives1
- Jacob H. Gerbrick, Photographer, Records1
- John Burns Murphy, Compiler, Genealogy of Murphy and Related Families1
- Patrick Ward Gainer (1904-1981), Collector, Papers1